2024
Alvarado Obando M, Rey-Valera D, Cava F, Dörr T. 2024. Genetic Interaction Mapping Reveals Functional Interactions between Endopeptidases and Carboxypeptidases. PLOS Genetics
Lee J, Jha K, Harper CE, Zhang W, Ramsukh M, Bouklas N, Dörr T, Chen P, Hernandez CJ. 2024. Determining the Young’s Modulus of the Bacterial Cell Envelope. ACS Biomater Sci Eng
2023
Harper CE, Zhang W, Shin JH, Keller M, van Wijngaarden E, Chou E, Lee J, Wang Z, Dörr T, Chen P, Hernandez CJ. 2022. Mechanical Stimuli activate gene expression via a cell envelope stress sensing pathway. Scientific Reports 13: 13979
Keller M, Han X, Dörr T. 2023. Disrupting Central Carbon Metabolism increases antibiotic susceptibility in Vibrio cholerae. Journal of Bacteriology https://doi.org/10.1128/jb.00476-22
Keller M, Dörr T. 2023. Bacterial metabolism and susceptibility to cell wall-active antibiotics. Advances in Microbial Physiology 83
Dörr T. 2023. Cleave a Septum, leave a Cell: Bdellovibrio bacteriovorus secretes a specialized lytic transglycosylase to clear prey cell septum obstruction, Journal of Bacteriology
Dörr T.. 2023. Bacterial Physiology: A novel periplasmic glucan promotes cell envelope stress management. Current Biology 33(2)
Weaver A, Taguchi A, Dörr T. 2023. Masters of Misdirection: Peptidoglycan Glycosidases in Bacterial Growth. Journal of Bacteriology doi: 10.1128/jb.00428-22.
2022
O’Leary MK, Sundaram V, LiPuma JL, Dörr T, Westblade LF, Alabi CA. 2022. Mechanism of Action and Resistance Evasion of an Antimicrobial Oligomer against Multidrug-Resistant Gram-Negative Bacteria. ACS Appl. Bio Mater.
Islam N, Kazi MI, Kang KN, Biboy J, Gray J, Ahmed F, Schargel RD, Boutte CC, Dörr T, Vollmer W, Boll JM.2021. Peptidoglycan recycling contributes to outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii. MBio 13(3)
Weaver AI, Alvarez L, Rosch KM, Ahmad A, Wang GS, VanNieuwenhze MS, Cava F, Dörr T. 2022. Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products. eLife 11:e73178
Ghosh S, Mohamed Z, Shin JH, Bint E Naser SF, Bali K, Dörr T, Owens R, Salleo A, Daniel S. 2022. Impedance Sensing of Antibiotic Interactions with a Pathogenic E. coli Outer Membrane Supported Bilayer. Biosensors and Bioelectronics204:114045
Murtha AN, Kazi, MI, Schargel RD, Cross T, Fihn C, Carlson EE, Boll JM, Dörr T. 2022. High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications. Plos Pathogens
2021
Li Y, Cross T, Dörr T. 2021. Analysis of AcrB in Klebsiella pneumoniae reveals natural variants promoting enhanced multidrug resistance. Research in Microbiology (in press)
Dörr T. 2021. Understanding tolerance to cell wall-active antibiotics. Annals of the NY Academy of Sciences 1496(1)
Ellner S, Buchon N, Dörr T, Lazzaro BP. 2021. Host-pathogen Immune Feedbacks Can Explain Widely Divergent Outcomes from Similar Infections. Proceedings of the Royal Society B 288: 20210786.
Shin JH, Choe D, Ransegnola B, Hong HR, Onyekwere I, Shi Q, Cho BK, Westblade LF, Brito IL, Dörr T. 2021. A multifaceted cellular damage repair and prevention pathway promotes high level tolerance to beta lactam antibiotics, EMBO Reports 22(2)
2020
Westblade LF, Errington J, Dörr T. 2020. Antibiotic Tolerance. Plos Pathogens 16(10)
Shin JH, Lanz M, Smolka MB, Dörr T. 2020. Characterization of an anti-FLAG binding protein in Vibrio cholerae. Biochemical and Biophysical Research Communications 528(3)
Shin JH, Sulpizio A, Kelley A, Alvarez L, Murphy SG, Fan, L, Cava F, Mao Y, Saper MA, Dörr T. 2020. Structural basis of peptidoglycan endopeptidase regulation. Proceedings of the National Academy of Sciences USA 117 (21)
Hernandez SB, Dörr T, Waldor MK, Cava F. 2020. Modulation of peptidoglycan synthesis by recycled cell wall tetrapeptides. Cell Reports 31 (4)
2019
Dörr T, Moynihan PJ, Mayer, C. 2019. Editorial: Bacterial Cell Wall Structure and Dynamics. Frontiers in Microbiology. doi: 10.3389/fmicb.2019.02051
Weaver AI, Jimenez-Ruiz V, Tallavajhala SR, Ransegnola BP, Wong KQ, Dörr T. 2019. Lytic transglycosylases RlpA and MltC assist in Vibrio cholerae daughter cell separation. Molecular Microbiology https://doi.org/10.1111/mmi.14349
Cross T, Ransegnola BP, Shin JH, Weaver AI, Fauntleroy K, VanNieuwenhze M, Westblade LF, Dörr T. 2019. Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens. Antimicrobial Agents and Chemotherapy DOI: 10.1128/AAC.00756-19
Murphy SG, Alvarez L, Adams MC, Liu S, Chappie JS, Cava F, Dörr T. 2019. Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response.
2018
Hubbard TP, Billings G, Dörr T, Sit B, Warr AR, Kuehl CJ, Kim M, Delgado F, Mekalanos JJ, Lewnard JA, Waldor MK. 2018. A live vaccine rapidly protects against cholera in an infant rabbit model. Science Translational Medicine: 10(445),eaap8423
Weaver AI, Murphy SG, Umans U, Tallavajhala S, Onyekwere I, Wittels S, Shin JH, VanNieuwenhze M, Waldor MK, Dörr T. 2018. Genetic determinants of penicillin tolerance in Vibrio cholerae. Antimicrobial Agents and Chemotherapy: 01326-18
2017
Zhao H, Patel V, Helmann JD, Dörr T. 2017. Don’t let sleeping dogmas lie: New views of peptidoglycan synthesis and its regulation. Molecular Microbiology: 106(6), pp. 847-860
Beckwith J, Bergman K, Carson MJ, Dörr T, Geller L, Pierce R, Krimsky S, Martin C, Santiago M, Vashlishan Murray A, Warren C, Zichterman C. 2017. Using Dialogues to Explore Genetics, Ancestry and Race. American Biology Teacher: 79(7)
Yamaichi Y, Dörr T. 2017. Transposon Insertion Site Sequencing for Synthetic Lethal Screening. Methods Mol Biol: 1624: 39-49
2016 and earlier
Dörr T, Delgado F, Umans BD, Gerding MA, Davis BM, Waldor MK. 2016. A transposon screen identifies genetic determinants of Vibrio cholerae resistance to high molecular weight antibiotics. Antimicrobial Agents and Chemotherapy: 60(8)
Dörr T, Alvarez L, Delgado F, Davis BM, Cava F, Waldor MK. 2016. A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta lactam tolerance. Proceedings of the National Academy of Sciences USA: 113(2)
Dörr T, Davis BM, Waldor MK. 2015. Endopeptidase-mediated beta lactam tolerance. PLOS Pathogens: 11(4)
Möll A, Dörr T, Alvarez L, Davis BM, Cava F, Waldor MK. 2015. A D,D Carboxypeptidase is required for Vibrio cholerae halotolerance. Environmental Microbiology: 17(2)
Möll A, Dörr T, Alvarez L, Chao MC, Davis BM, Cava F, Waldor MK. 2014. Cell separation in Vibrio cholerae is mediated by a single amidase whose action is modulated by two non-redundant activators. Journal of Bacteriology: 196(22)
Dörr T, Lam H, Alvarez L, Cava F, Davis BM, Waldor MK. 2014. A novel peptidoglycan binding protein crucial for PBP1a-mediated cell wall biogenesis in Vibrio cholerae. PLoS Genetics: 10(6)
Dörr T, Möll A, Cava F, Lam H, Chao, MC, Davis BM, Waldor MK. 2014. Differential requirement for PBP1a and PBP1b in in vivo and in vitro fitness of Vibrio cholerae. Infection and Immunity: 82(5)
Dörr T, Cava F, Lam H, Davis BM, Waldor MK. 2013. Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae. Molecular Microbiology: 89(5)
Gurnev PA, Ortenberg R, Dörr T, Lewis K, Bezrukov SM. 2012. Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers. FEBS letters: 586(16)
Dörr T, Vulic M, Lewis K. 2010. Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. PloS Biology: 8(2)
Dörr T, Lewis K, Vulic M. 2009. SOS response induces persistence to fluoroquinolones. PloS Genetics: 5(12)